2300 Humas A Day

What follows are two articles about recent work performed by Dr. Frank Bastian and a response by Frank

Although Dr. Frank Bastian's research concerning Chronic Wasting Disease (CWD) has not been able to be replicated by other researchers, the Unified Sportsmen of Pennsylvania (USP) is continuing to support his research.

To review: Bastian believes that spiroplasma bacteria cause CWD in deer and other cervids. Conventional research has determined that misfolded proteins called prions cause CWD. Bastian believes that the prions are byproducts of the bacterial action.

For a number of years, Bastian has said that the first thing his research will develop is a kit that will allow hunters to test harvested deer for CWD in the field. The second thing he believes he can do is to develop live-animal tests and vaccines for CWD. This would be a great help for the deer-farming industry in dealing with CWD. He also thinks he can develop an oral vaccine that can be used for free-ranging deer. Another thing he believes he can do is to develop human antibiotic vaccines to cure and prevent the impacts of Creutzfeldt-Jakob disease that affects humans in the manner that Chronic Wasting Disease affects deer.

However, Bastian has been telling us these things for a number of years, but so far they have not come to pass.

Still, the USP, which is probably the most loyal supporter of deer hunters and deer hunting in Pennsylvania, has thrown its full support behind Bastian's research. After Bastian left Louisiana State University, he was able to set up another CWD research laboratory last June at the Advanced Materials Research Institute at the University of New Orleans. This is part of a partnership program known as the North American CWD Project that will be directed by highly regarded wildlife researcher John Eveland. Bastian is director of the privately operated Bastian Lab and has been granted a research professorship at the university, according to Eveland.

Bastian has joined forces with the Terra Cor Institution, a non-profit group, and several sportsmen's groups that support his research. The Terra Cor group is siting a second disease-control center in Pennsylvania, according to the fall issue of "Pennsylvania Woods and Waters," USP's newsletter. Also of note, besides the USP, the Allegheny County Sportsmen's League of Pennsylvania is a supporter of Bastian's research.

According to "Pennsylvania Woods and Waters," a million-dollar grant was approved by the Pennsylvania state government for the Pennsylvania center but has not been released by the governor.

If you want to support Bastian's research, you can mail a check made out to "USP" to Douglas Tyger, Treasurer, 184 Fairview Road, Kersey, PA 15846-9210.


Dr. Bastian just forwarded me your article from yesterday. I thought I'd send you a few thoughts while we're all holed up at home trying to survive another microbial nightmare. (I actually had to look it up not long ago to make sure that viruses could be classified as microbes.)

Not so many years ago, I watched as CWD was entering Pennsylvania and beginning to spread across the state without resistance as it had done successfully across America for the past half century. I have had significant experience with novel, virulent diseases of cervids in that as a young biologist at Penn State I discovered and conducted research on the brainworm disease in our Pennsylvania elk herd. Considering this, I realized that a malformed protein (prion) was not likely the culprit to be causing CWD, and began a search for another possibility. A research team at Yale had spent decades looking at a viral cause for CWD and other related transmissible spongiform encephalopathies (TSEs) of animals and humans, and concluded that while a virus was not the cause, neither was a misformed protein.

I discovered Frank Bastian a few years ago, and spent at least a year looking into his work and talking with him. I concluded that Frank had, in fact, cracked the CWD nut wide open and had made what will someday be recognized as a paradigm-shifting medical breakthrough. As you have written, I formed partnerships and set in motion a project that I hoped would quickly give us the microbial treatments to finally control and place CWD in remission in Pennsylvania and across America.

When kicking off our project at our press release in the Capitol Rotunda about a year ago, I made a bold prediction that we would have diagnostic test kits and vaccines in about a year. At the time, I was aware of the resistance from the mainstream prion camp that Dr. Bastian had experienced for many years toward moving his work forward, but had not yet experienced it. Having it to do over, I would now qualify my statement by saying that our research timeline was dependent on the acquisition of adequate funding and samples of infected deer. Getting both has been a challenge, to say the least. However, now that we're a year into our project I give no apology for making such a bold claim considering that after about a half century of research the mainstream prion industry has moved the bar not one inch closer to our understanding of CWD let alone coming up with vaccines to control and eradicate the disease. In fact, now that we have had time to assemble a blue-ribbon team of expert biomedical scientists from the medical schools at LSU, Tulane, and 8-10 other universities and private companies across the country who have peer-reviewed Dr. Bastian's research and realize that he holds the answer, I am now even more bold in my statement that we can have diagnostic kits and vaccines within 8-16 months -- with adequate funding and samples.

Richard, there is much more at stake regarding Dr. Bastian's discovery than just CWD -- not that this is a trivial endeavor. There are an estimated 15,000 CWD-infected deer that are being eaten by hunters and their families each year. Considering the number of family members and friends who might be eating these CWD-infected deer, we could be looking at a rapidly growing reservoir of humans who are at grave risk in the future. Dr. Bastian's diagnostic cervid test kit would provide hunters with an immediate test in the field at the point of harvest as to whether their deer are infected -- preventing them from eating infected animals. The current prion-based test takes weeks and longer at which time deer could be partially consumed. However, a test that is based on prions does not mean that a deer that tests negative is not infected in that it could be incubating Dr. Bastian's bacterium and real cause of the disease for 12 months or more before prions manifest. His diagnostic human test kit will allow hunters to test themselves and their families for possible infection. Now let's throw in a bacterial-based live-animal test and vaccines. Currently proposed research on a prion-based live-animal test will be practically useless in that a negative-testing deer could have been harboring the bacterium for a year.

Two weeks ago, we doubled the size of our New Orleans' lab thanks to the hard work of Unified Sportsmen and Allegheny County Sportsmen's League in providing much needed funding. This action is intended to set the stage for moving more rapidly on solving the CWD epidemic, but especially to prepare for research on related human neurological diseases. These diseases are now resulting in the deaths of about 2,300 humans per day, and Dr. Bastian has isolated the cause of one of these human TSE diseases as being caused by his previously unknown bacterium with a strong indication that some or all of this group of human neurodegenerative diseases are caused by his Spiroplasma sp. bacterium. These diseases include Creutzfeldt-Jakob Disease (CJD), Parkinson's, ALS or Lou Gehrig's Disease, and Azheimer's. They say there's a new Alzheimer's patient diagnosed every 68 seconds, and no one ever survives AD. We all should be encouraging and supporting the research of Dr. Bastian considering the magnitude of the crises that he is trying to address.

Personally, I am now at the age that I would like to be fishing with my grandkids. Instead, I am compelled to assist Dr. Bastian in anyway possible to see that this project succeeds. I could not live with myself if I turned my back on not only a solution to CWD, but toward saving tens, hundreds, and possibly millions of people per year.

Like COVID-19, we have been and continue to face another microbial outbreak for which we have scratched our heads and accepted failure in a solution for a century and more while many millions of people have died from these always-fatal neurological diseases. It's difficult now competing with COVID-19 for funding and interest, but today 2,300 people and their families wish that this were not the case, and another 2,300 tomorrow.


 

Frank responded:

We have two problems.

Money- funding agencies are all supporting the failed prion theory. I have uncovered a scary extreme thermoacidophilic bacterium that is far more important than the corona virus ( which will likely die out before vaccines are available)TSE samples. The USDA and Wildlife agencies are hoarding CWD samples. The only ones with access are the prion groups because of governmental bias,. They have a transfer agreement which the Universities will not sign since it impinges on academic freedom and patent rights. Their main emphasis is on lowering deer numbers with sharpshooters and ways to dispose of the bodies.My Pennsylvania support group have run into political roadblocks regarding both funding and availability of samples

What a mess. If you have a billionaire friend who is interested ion preventing a disaster in the wildlife population, send him my way.

Your support is appreciated and encourages me to continue this quest although at times the future appears bleak in spite of our success. One friend joked that my research will be rediscovered 10 to 20 years after I quit the quest.

Regards,

Frank

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Research Continues in the Cause of CWD

 

Chronic wasting disease is a growing threat for deer, elk, and moose in North America, infecting a larger portion of the populations each year.

The fatal disease attacks the neurological system and seems, at this point, impossible to cure. Adding another layer to this complicated issue is a recent discovery that might indicate that efforts to stop it have been misaligned, with silver-lined implications that could have dire consequences if not heeded.

 

Read the rest of the article HERE.

 

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Major NIH grant will support early diagnosis of Parkinson's disease via skin testing

CLEVELAND, October 4, 2019--Wenquan Zou, MD, PhD, an expert in degenerative neurological diseases, along with his collaborators Shu G. Chen, PhD also from the Case Western Reserve University School of Medicine, Jiyan Ma, MD, PhD, from Van Andel Institute in Grand Rapids, Michigan, and Thomas Beach, MD, PhD, from Banner Sun Health Research Institute, Sun City, Arizona, have received a five-year, $3.6 million grant from the National Institutes of Health for diagnosing Parkinson's disease (PD) via an innovative skin testing approach. Also part of the team is Steven Gunzler, MD, a neurologist at the University Hospitals Cleveland Medical Center and the School of Medicine.

The methodology uses highly sensitive technology to detect the presence in the skin of "misfolded" alpha-synuclein (α-Syn) proteins that are the cause of nerve cell dysfunction and death in PD.

 

Read the rest of the artice HERE.

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Phage therapy: A different approach to fighting bacteria

What is Phage therapy? 

Phage therapy (PT) is also called bacteriophage therapy. It uses viruses to treat bacterial infections. Bacterial viruses are called phages or bacteriophages. They only attack bacteria; phages are harmless to people, animals, and plants.

Bacteriophages are the natural enemies of bacteria. The word bacteriophage means “bacteria eater.” They’re found in soil, sewage, water, and other places bacteria live. These viruses help keep bacteria growth in check in nature.

Phage therapy might sound new, but it has been used for 100Trusted Source years. However, the treatment isn’t well known. More research is needed on bacteriophages. This therapy for disease-causing bacteria may be a useful alternative to antibiotics.

 

Read the rest of the article HERE.

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Novel Spiroplasma sp. Isolated From CWD

Novel Spiroplasma sp. Isolated From CWD Is an Extreme Bacterial Thermoacidophile That Survives Autoclaving, Boiling, Formalin Treatment, and Significant Gamma Irradiation

Abstract


Rapid spreading of chronic wasting disease (CWD) in wildlife and captive cervid populations has exposed lack of progress in deal- ing with the transmissible spongiform encephalopathies (TSE) of man and animals. Since the TSE transmissible agent was resistant to extremes in environmental and chemical treatments, focus was on an unconventional agent including the prion theory. Recent break- through research has revealed consistent isolation of a novel Spiro- plasma sp. from TSE-affected tissues that propagates in cell-free media and on agar. Here, we developed a live culture assay to test whether the CWD spiroplasma isolate possessed unconventional bi- ologic properties akin to those of the transmissible agent of TSE.

 

View the online abstract HERE. 

Download the full article HERE.

 

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